Daily Editorial Cloze Test Quiz – 26

Editorial Cloze Test Quiz

Scientists have for the first time managed to edit genes in a human embryo to repair a genetic mutation, fuelling hopes that such procedures may one day be available outside laboratory conditions. In results announced in Nature this week, scientists fixed a mutation that thickens the heart muscle, a condition called hypertrophic cardiomyopathy. The cardiac disease causes ______(1)_______death in otherwise healthy young athletes and affects about one in 500 people overall. It is caused by a mutation in a particular gene and a child will suffer from the condition even if it inherits only one copy of the mutated gene. Correcting the mutation in the gene would not only ______(2)_______that the child is healthy but it would also prevent the mutation from _______(3)________on to future generations. In an attempt to remove the small portion of mutation, the researchers injected sperm of a man affected by hypertrophic cardiomyopathy and the gene-editing tool called CRISPR-Cas9, that cuts the DNA near the position of the mutation, into the egg at the same time. The gene-editing tool cut the DNA at the correct position in all embryos and 42 out of the 58 embryos did not carry the mutation. Though the research marks a major milestone in genome editing of embryos, it will be a long while before it _______(4)_______available as a tool to produce healthy embryos. For instance, even research on embryos using federal funding is not permitted in the U.S., where the research was carried out. The embryos were produced with the clear ______(5)_______of using them solely for research and not for implanting them in women.

Editorial Cloze Test Quiz

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